Publications

Found 10 results
2015
van der Wel T, Janssen FJ, Baggelaar MP, Deng H, Dulk Hden, Overkleeft HS, van der Stelt M.  2015.  A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α. Journal of Lipid Research. 56(4) 927-935.
2014
Janssen FJ, Deng H, Baggelaar MP, Allarà M, van der Wel T, Dulk Hden, Ligresti A, van Esbroeck ACM, McGuire R, Di Marzo V et al..  2014.  Discovery of Glycine Sulfonamides as Dual Inhibitors of sn-1-Diacylglycerol Lipase α and α/β-Hydrolase Domain 6. Journal of Medicinal Chemistry. 57(15) 6610-6622.
Benson N, Metelkin E, Demin O, Li GL, Nichols D, van der Graaf PH.  2014.  A Systems Pharmacology Perspective on the Clinical Development of Fatty Acid Amide Hydrolase Inhibitors for Pain. CPT: Pharmacometrics Systems Pharmacology. 3(1) e91.
2013
Baggelaar MP, Janssen FJ, Esbroeck ACM, Dulk H den, Allarà M, Hoogendoorn S, McGuire R, Florea BI, Meeuwenoord N, van den Elst H et al..  2013.  Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain. Angewandte Chemie International Edition. 52(46) 12081-12085.
Akhtar MT, Ali S, Rashidi H, van der Kooy F, Verpoorte R, Richardson MK.  2013.  Developmental Effects of Cannabinoids on Zebrafish Larvae. Zebrafish. 10(3) 283-293.
2012
Wei H, Hu C, Wang M, van den Hoek AM, Reijmers TH, Wopereis S, Bouwman J, Ramaker R, Korthout HAAJ, Vennik M et al..  2012.  Lipidomics Reveals Multiple Pathway Effects of a Multi-Components Preparation on Lipid Biochemistry in ApoE*3Leiden.CETP Mice. PLoS ONE. 7(1) e30332.
2011
van der Stelt M, Cals J, Broeders-Josten S, Cottney J, van der Doelen AA, Hermkens M, de Kimpe V, King A, Klomp J, Oosterom J et al..  2011.  Discovery and Optimization of 1-(4-(Pyridin-2-yl)benzyl)imidazolidine-2,4-dione Derivatives As a Novel Class of Selective Cannabinoid CB2 Receptor Agonists. Journal of Medicinal Chemistry. 54(20) 7350-7362.
Ali S, Champagne DL, Spaink HP, Richardson MK.  2011.  Zebrafish embryos and larvae: A new generation of disease models and drug screens. Birth Defects Research Part C: Embryo Today: Reviews. 93(2) 115-133.
2005
van der Stelt M, Trevisani M, Vellani V, De Petrocellis L, Moriello ASchiano, Campi B, McNaughton P, Geppetti P, Di Marzo V.  2005.  Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels. The EMBO Journal. 24(17) 3026-3037.
2003
Marsicano G., Goodenough S., Monory K., Hermann H., Eder M., Cannich A., Azad S.C, Cascio M.G, Gutierrez S.O, van der Stelt M. et al..  2003.  CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science. 302 84-88.